Second Covid Vaccine Booster Got Any Mojo?

Tomorrow’s April Fool’s Day and I thought I’d get this post up today so it wouldn’t get confused with a joke.

I’m genuinely a little confused about the FDA and CDC approval of the 2nd Covid vaccine booster. It’s almost like this vaccine is getting a mojo of some kind, at least with some experts.

Although I’m not keen on getting another jab, I’ll do it if there is reasonable evidence to support it. Not everyone on the FDA Advisory committee is for it. Dr. Paul Offit was quoted in a news story as saying, “We’re going to have to learn to live with mild disease at some point.” 

Dr. Offit is the director of the Vaccine Education Center at Children’s Hospital of Philadelphia. I’ve heard him speak at FDA Advisory Committee meetings during public Zoom meetings on the subject and I respect his opinion. He doesn’t think frequent boosting is a reasonable thing to do. I’m inclined to agree with his opinion that most people won’t do it anyway. I’m sure he’ll have more to say at the April 6 FDA Covid Vaccine Advisory Committee meeting.

I was not surprised to learn that of the 90 million Americans who got their initial Covid vaccine series, only about half got the first booster. What kind of mojo is that?

Even the Pfizer drug company CEO, Albert Bourla, says frequent boosting is impractical.

There is some serious doubt in my mind about the booster mojo. Sena says that it would be helpful if more local infectious disease experts would express their own opinions about the direction this vaccination strategy is going. She has a point.

Does the Covid vaccine booster have any mojo? What do you think?

Featured image picture credit: pixydotorg.

Get Happy Now

I think nearly all of us would agree that the last two years have been especially hard on the human race. It’s tough to be happy. Or would it be better to say it’s tough to find happiness? Or should you say that there are few things to be happy about?

What I’m getting at is the difficulty in defining the term “happiness.” I’m sometimes very unhappy. But the intensity doesn’t last. And I’m happier when I’m writing. I’m one of those who thinks happiness is a byproduct of what we do. But a movement has been under way for years to define happiness scientifically.

What’s new on the horizon? Sena found a news story about a New Jersey college offering the world’s first Master of Arts level online degree program in Happiness Studies. It’ll cost you only $17,700 according to the Centenary University web page about it (accessed March 26, 2022).

The course is four months and worth 30 credits. I’m no judge on whether it’s worth the hefty price tag.

The program will be directed by Dr. Tal Ben-Shahar, a teacher and writer in the areas of leadership and positive psychology. He looks happy. He’s very successful.

The program at Centenary is not the only game in town, though. This is just web clicking research, mind you, but there is The Science of Happiness Course based at Berkeley University of California (of course it’s in California!). It was launched in 2014. Like the Centenary program, it’s led by celebrity star level teachers from the school’s Greater Good Science Center: Emiliana Simon-Thomas, PhD (the director), and founder Dacher Keltner, PhD, author of best-seller Born to be Good (which I’ve never read). There is a free 8-week audit level Science of Happiness course available although you can earn a certificate by working a little harder, taking exams and paying $169.

Positive psychiatry has been championed by psychiatrist, Dr. Dilip Jeste, as he outlined his thoughts on it in Psychiatric Times (Positive Psychiatry: An Interview With Dilip V. Jeste, MD, February 22, 2016, Renato D. Alarcón, MD, MPH, Psychiatric Times, Vol 33 No 2, Volume 33, Issue 2). Some of his interesting comments give the impression you could overdo it:

Currently, there is no substitute for using DSM-5 and ICD-10 diagnoses that are required by Medicare and private health insurers and also for communication with various other health care systems. The positive psychiatry approach involves additional notations about the patient’s level of well-being and perceived stress along with strengths, including resilience, optimism, and social engagement. Validated rating scales for these measures are available and practical. This more complete depiction of a patient’s mental health is of much greater value for holistic management than just a DSM-5 diagnosis. The information obtained from these ratings may be shared with the patient and his or her family, and revisited during subsequent visits to document progress.

Positive psychiatry’s principles can be incorporated in a reformulation of behavioral or psychosocial interventions, whether they are supportive, psychodynamic, cognitive-behavioral, or another type. The goal is to enhance positive psychosocial characteristics to improve well-being, in addition to reducing symptoms and preventing relapse-which are at the core of traditional psychiatry.

There are, however, a few limitations to positive psychiatry-such as the potential social/political and ethical implications of the unbridled promotion of positive psychosocial characteristics. For example, one may appropriately object to the notion that optimism should be universally promoted through biological or other interventions. Therefore, a balanced approach to behavior modification is warranted.

He thought you could object to the idea that optimism should be the overriding goal. “The unbridled promotion of positive psychosocial characters.” Oops, I just noticed my mistake in using the word “characters” instead of “characteristics.” I corrected it and then thought it was probably just a Freudian slip, so I changed it back. What the heck.

That reminded me of a paper I read many years ago about adding a new psychiatric disorder to the Diagnostic and Statistical Manual for Mental Disorders (DSM): Major Affective Disorder, pleasant type. I think some people missed the satire in this article (Bentall RP. A proposal to classify happiness as a psychiatric disorder. J Med Ethics. 1992 Jun;18(2):94-8. doi: 10.1136/jme.18.2.94. PMID: 1619629; PMCID: PMC1376114.)

Bentall was objecting to the methods employed by the committees putting the DSM together, specifically how they decided on what is or is not a disease. I think the DSM-IV was in the preparation stage at the time he wrote the article.

I liked the response of one blogger to Bentall’s paper. The title of the post was “Major Affective Disorder, Pleasant Type” and subtitled “Cancer and Attitude.” She was diagnosed with pancreatic cancer and coping with it, not with unbridled positivity, but with a realistic, balanced outlook:

“But I don’t believe a positive attitude means that I am happy all the time. I like to think of myself as a positive realist. I have accepted that each day I live is an actual gift and I truly may not be here in 6 months or a year.”

“But I’ve also been very angry about it, and many times feel sad and hopeless. Being positive just means you believe in tomorrow. And I do believe I will be here tomorrow.”

I think I’m happy with letting her have the last word here.

FDA Advisory Committee Meeting on Covid Vaccine Boosters Scheduled for April 6, 2022

The FDA Advisory Committee on Vaccines and Related Biological Products has scheduled a meeting on April 6, 2022 “to discuss considerations for use of COVID-19 vaccine booster doses and the process for COVID-19 vaccine strain selection to address current and emerging variants.” The meeting will run from 8:30 AM-5:00 PM ET.

Mydriatic Madness

I got my eyes examined yesterday. They put mydriatic drops in like they usually do. It’s been a while since my last exam. I remember a long time ago the eye clinics used to give you a free pair of those flimsy paper sunglasses to cut down on the glare and blurriness. I see them going on Amazon for $30-$60 bucks for 50-100 count boxes.

Anyway, they put the mydriatic drops in and after a few minutes, I was blind as a bat. I had to use the restroom and ended up talking to a mop for a couple of minutes. I thought it was strange that a skinny old guy would wear gray dreadlocks.

When I got back in the hallway, I was somewhat disoriented. I walked up and down the hall and must have got off on a side route somehow. I stopped next to a counter, just trying to get my bearings and a guy wearing a white cap asked me,

“Sir, would you like a corn dog? It’s made from plants!”

I said, “Hm, how much?”

“Only $15.99!”

“Excuse me while I check your rating with the Better Business Bureau.”

His face looked like it was starting to drip.

I walked briskly away and eventually found myself in a dark, blurry hallway. I stumbled through a swinging door and heard somebody exclaim,

“Oh no, the surgeon just fainted! Quick, get that guy scrubbed and gowned!”

I haven’t been in surgical garb since medical school, and never that fast. I was a little concerned and asked,

“How did you drag the surgeon out so quickly?”

A scrub nurse snapped, “Doctor, it’s an emergency penectomy! Here.”

Everything was blurry. Something slapped into my hand and it had a trigger. When I pressed it, there was a noise like a mini buzz saw.

“Can anyone direct me back to the eye clinic?”

“Hurry, doctor, it’s about to burst!”

Somebody bumped my arm, and I heard a scream. I said,

“Isn’t the patient anesthetized?”

“Doctor, you got the scrub nurse!”

The floor was getting slippery for some reason and I stumbled to my hands and knees. I managed to get out of the operating room. When I got to my feet, I ditched the scrubs but kept the skull cap because it had some nice red spots on it. Skull caps are usually pretty drab.

I heard somebody shout, “Call Security! The guy is wearing a bloody skull cap!

I sure didn’t want to run into that guy, so I veered into a brightly lit hallway away from all the noise. Bright lights worsen the glare you get after mydriatic drops, so I had even more trouble seeing. It led to what turned into an elevator. It was full of people in dark clothes. When the elevator stopped, I could feel the wind. Apparently, we were on the roof. There was a deafening whirring noise. I had to yell over it,

“Am I anywhere close to the eye clinic?”

“Don’t worry, doctor, remember to duck your head as you board the helicopter. We have to move fast!”

The view of the hospital campus is spectacular from the air. When the air ambulance attendants realized their mistake, they lowered me in a basket back down to the door outside the eye clinic. I was glad to get back inside because it gets a little chilly in a helicopter.

Anyway, to make a long story short (too late!) I got squared away with, among other things, a new prescription for eyeglasses and a fine for practicing surgery without a license.

I had no trouble finding my way back to the parking ramp. Horns were honking everywhere. Everybody was pressing their car key fobs to find their vehicles. I think most of them were leaving the eye clinic.

Picture credit: Pixydotorg.

Don’t Look in the Dictionary for Mental Health and Mental Illness

I read an interesting article in Clinical Psychiatry News the other day, written by Dinah Miller, MD in the Shrink Rap News column, “Psychiatry and semantics.” Dr. Miller’s point was that it’s sometimes hard to define terms when discussing mental illness and stress.

Can stress be defined as a mental illness? What the heck is the definition of mental illness? What does it mean to say that someone is depressed?

Way back in 2006, when I was an Associate Professor in psychiatry, I wrote an introductory article for a series of articles about stress for Psychiatric Times. The title was “Stress and the Psychiatrist: An Introduction.” I had a tough time defining stress also. In fact, the first 2 paragraphs of my article say it all:

“Defining “stress” and how it is expressed and managed in both psychiatrists and patients is a difficult proposition. This Special Report focuses on stress and the middle ground between the impulse to say there is no such thing as “stress” and the tendency to describe many explicit addressable issues under the monolithic term, “stress.”

I remember what my ward supervisor once told me about stress when I was a resident in psychiatry. I was presenting a case about a patient who was depressed and complaining about all the stress in her life. At that point, he barked testily, “There’s no such thing as stress!” He went on to direct me to be more specific in my interviewing techniques in an effort to identify the concrete problems that my patient was experiencing, instead of substituting a sort of shorthand (i.e., “lazy”) method of indicating the source of her depression. In his view, the term “stress” was being overused and it had become virtually meaningless.”

At the time I wrote that article, there was surprisingly little data about stress in psychiatrists. On the other hand, it was well known that psychiatrists are prone to stress, burnout, and suicide.

As I read my own article, I was surprised at how little things have changed over the years. In fact, they have gotten much worse. There is a lot of talk about The Great Resignation. Health care workers are leaving their jobs in droves, often due to the pressures of the pandemic.

I was and still am a fan of Stephen Covey’s wisdom:

Covey disparages the “Great Jackass” theory of management, in which the carrot-and-stick style of leadership dominates. Adopting a principle-centered leadership paradigm entails a commitment to change at the individual level, working from the inside out. This means building self-awareness, identifying one’s own vitally important goals, and creating a balance that includes a devotion to living, loving, learning, and leaving a legacy. In turn, this might lead to identifying a personal mission and a vision for an organization that empowers others to find their own motivation to service. Many of the problems that Covey finds in big business exist in the mental health care sector-low trust, low productivity, and environments in which the cultures of blame and victimization, political gamesmanship, and apathy spread. These are often the issues that get subsumed under the name of “stress” in academic departments, community mental health centers, and private practice groups.

Of course, despite how wise I sounded back then, I still ended up with burnout. It took a lot out of me, but it didn’t destroy me.  According to some figures, about 40%-60% of physicians are burned out.

One guy I admire a great deal is Dr. George Dawson, MD. He writes the blog Real Psychiatry. He has been fighting the pressures in the health care system for decades and signs that he’s still going strong are in the Psychiatric Times article “The Bureaucratic Takeover of American Psychiatry: George Dawson, MD, DFAPA.

The interviewer for that article, Dr. Awais Aftab, MD asked George what he thought about the system that psychiatrists must work in which tends to discount the effect of social adversity, poverty, and trauma on the psychiatric distress of their patients, yet corner them into a pill-prescribing role.

George replied, “I heard repeated stories about how child psychiatrists and pediatricians were expected to provide a miracle medical cure to address complex psychosocial problems.

As the number of prescriptions increased there was concern that children were being overmedicated and treated with inappropriate prescriptions like atypical antipsychotics. At that point a consultation line with a child psychiatrist was provided for these prescribers to discuss the prescriptions. At no point were the psychosocial parameters addressed and they still have not been addressed to this day.”

In response to Dr. Aftab’s question about George’s recommendations for how to address this situation:

“I have been writing and speaking about this in various capacities for the past 30 years. During this time very few physicians have been interested in a political fight. The only major figure in psychiatry I can recall is Harold Eist, MD, when he was the president of the American Psychiatric Association. Practically all other professional organizations are silent about managed care and pharmacy benefit managers as malignant forces. There is a lot written about burnout and how these companies waste physician time to the tune of billions of dollars a year. Nobody seems to talk much about all the free work physicians have to do to support the conflict-of-interest-driven decisions these companies make. There is some current interest in the Maintenance of Certification (MOC) issue that professional organizations have also ignored. But in general, nothing will happen until many more physicians get activated and unite. There is still the escapist dream out there that “I can still do private practice,” but that is vanishing fast.

After decades of elaborate planning and recommendations, I am back to the beginning. The course of action at this point is fairly simple. There has to be united agreement on the fact that managed care companies and pharmaceutical benefit managers work against the best interests of physicians and their patients. Once that recognition is there, a rational course of action may follow. But it does take physician professional organizations taking a clear stand against these business practices.

I do think there is a lot to be said for specialty clinics that are outside of the administrative scope of managed care companies. The first groups I noticed were radiologists and anesthesiologists. They were followed by surgical specialists. I do not see many large free-standing psychiatric practices. I think it is possible to practice with a group of like-minded psychiatrists and provide excellent care based on an agreed upon practice style that will result in greater degree of professional satisfaction than is possible as an employee of a managed care company. The required business expertise and planning is a deterrent to most but knowing what I know about the landscape today I would have tried it much earlier in my career.”

George announced his retirement in January this year. But he’s not done.

Dr. Miller suggests that we come up with a lingo that’s more precise to clarify what mental illness and mental health are and what our positions as practitioners and patients ought to be—and what we should do.

So that naturally led me to Allen Frances, MD, who wrote the book on the subject several years ago, “Essentials of Psychiatric Diagnosis: Responding to the Challenge of DSM-5.” Dr. Frances was also interviewed by Dr. Awais Aftab, MD, leading to the article “Conversations in Critical Psychiatry: Allen Frances, MD, published in May of 2019.

Dr. Frances says this about what he believes is “among the noblest of professions”:

 “I fear that too many psychiatrists are now reduced to pill pushing, with far too little time to really know their patients well and to apply the rounded biopsychosocial model that is absolutely essential to good care. We also have done far too little to educate the primary care doctors who prescribe 80% of psychiatric meds on the principles of cautious prescribing, proper indications, full consideration of risks, and the value of watchful waiting and tincture of time.

 I despair the diagnostic inflation that results from a too loose diagnostic system, aggressive drug company marketing, careless assessment, and insurance company pressure to rush to judgement. Diagnoses should be written in pencil, and under-diagnosis is almost always safer and more accurate than over-diagnosis. And, finally, I object to the National Institute of Mental Health (NIMH) research agenda that is narrowly brain reductionistic; it has achieved great intellectual masterpieces, but so far has not yet helped a single patient. So, in sum, I have loved being a psychiatrist, but wish we were better organized to end psychiatric suffering.”

Essentials of Psychiatric Diagnosis by Allen Frances

He rejects the dichotomy that mental illnesses are either diseases or problems in living as far too simplistic.  He deplores the tendency of the DSM 5 to confuse mental disorder with “everyday sadness, anxiety, grief, disappointments, and stress responses that are an inescapable part of the human condition.” He says the DSM should be only a tool to help guide clinicians’ judgment, not replace it.

So, let’s stop stressing ourselves out looking in the dictionary for definitions of mental health and mental illness.

with permission from the publisher Guilford Press

Third Video in the Uncovering Hawkeye History Series: “Endless Innovation: An R1 Research Institution (1948-1997)”

Here’s the video recording of the third session in the Uncovering Hawkey History Series: Endless Innovation: An R1 Research institution (1948-1997).” Enjoy!

Video of UI Breaking Barriers: Arts, Athletics, and Medicine (1898-1947)

Here is The University of Iowa video of the presentations from the February 8, 2022 Uncovering Hawkeye History series (2nd in the series), celebrating the 175th anniversary of the University of Iowa beginnings in 1847. The audio is fine on this one.

Thoughts on “The Next Chapter: Blazing New Trails (1998-2047)

The final presentation of the series night before last, Uncovering Hawkeye History in honor of the 175th anniversary of the University of Iowa was a fascinating review of the changes in architecture of the campus, how local and national politics influenced the university and vice versa, as well as the expansion of the role of philanthropy to support its mission over the years. A YouTube video of the recorded presentation will be posted here at a later date.

There was not enough time to do much more than briefly mention the new trails being blazed by three leading programs. However, you can read more about them in Iowa Magazine.

Craig Kletzing is the principal investigator for NASA’s TRACERS mission. He’s a UI physics and astronomy professor who secured the largest research grant in the history of The University of Iowa in 2019 to study the interactions of the magnetic fields of the sun and the Earth.

Christopher Merrill is the director of the International Writing Program and professor of English. Merrill has made cultural diplomacy mission to over 50 countries. He once served on the U.S. National Commission for UNESCO and the National Council on the Humanities.

Dr. Patricia Winokur, the executive dean of the Roy J. and Lucille A. Carver College of Medicine, physician and professor of internal medicine—infectious diseases, and leader of Iowa’s Covid-19 vaccine clinical trials. Dr. Winokur is a nationally recognized leader in the field of infectious diseases. She created the UI Vaccine and Treatment Evaluation Unit, one of the top vaccine research programs in the country and one of only nine nationwide funded by the National Institute of Allergy and Infectious Diseases.

At the end of the presentations, university archivist David McCartney announced that he will be retiring as soon as next week. He wished everyone well and the presenters I’m sure all wish him well.

He has held the archivist position since 2001. He has led a very interesting and varied life. A story posted in The Academic Archivist on November 12, 2020 by Katie Nash, MLIS, CA reveals he got his undergraduate degree in journalism from the University of Wisconsin-Madison. He received his MA in history and MLS (master’s degree in library and information studies) in 1998, both from the University of Maryland at College Park.

He also was a reporter for radio stations in Alaska and the Midwest. I’ll bet that was interesting. He was between warehouse jobs in the summer of 1992 when he drove around the Midwest, researching Carrie Chapman Catt, the woman suffrage leader and founder of the League of Women Voters. It turns out Catt grew up near David’s hometown. That work led to publishing a collection of Catt’s papers in a catalog.

David has done a great many things. He believes that his profession’s worth and legitimacy are being challenged, and that the value of the work he and others do is often unrecognized. He firmly believes that institutions and corporations have to understand their responsibility to maintain a strong archives and records management program. He’s very motivated to advocate for his profession.

I probably would not have looked for any further information about David McCartney had he not announced his retirement at the close of the final presentation of this series. He made his point simply and humbly, saying the challenges of keeping up with the technology demands of his job were part of the reason for his retirement.

He even said he hoped he would see the presenters in the Ped Mall (officially named City Plaza), a pedestrian mall in downtown Iowa City near the UI campus, built in 1979 as the centerpiece of the city’s urban renewal project. It’s a popular gathering place for students and locals. There are concerts, jazz festivals, and art shows.

As a relatively recent retiree myself in June 2020 (19 months or 86 weeks or 606 days ago but who’s counting?), I can relate to David on this issue. Many of those I worked with were sad to see me go. I think many will be sad to see David go.

Next in The Series: The Next Chapter: Blazing New Trails (1998-2047)

The next and final presentation in The University of Iowa Hawkeye History series is entitled The Next Chapter: Blazing New Trails (1998-2047). I believe you can still register here.

It will be a Zoom presentation from 4:30-6:00 PM tomorrow, February 22, 2022. As in the previous presentations, the guide will be university archivist, David McCartney and will feature the following presenters:

Rod Lehnertz (02MBA), senior vice president for finance and operations

Lynette Marshall, UI Center for Advancement president and CEO

Peter Matthes (00BA, 14MBA), senior advisor to the president and vice president for external relations

Interesting highlights can be previewed below:

Milestones in University of Iowa History

Starting Over

Three Leading Professors on the future of The University of Iowa

Hope you can make it!