FDA Authorizes Updated mRNA Covid-19 Vaccines

Today, the FDA approved and authorized the updated mRNA Covid-19 vaccines, specifically for the monovalent XBB.1.5 variant.

See the announcement on the FDA website for full details. The CDC ACIP will meet to discuss clinically-based recommendations for the use of these vaccines tomorrow.

22nd Anniversary Commemoration of 9/11 Attacks

The 22nd Anniversary Commemoration of the 9/11 attacks and the 1993 World Trade Center will be observed today.

I remember where I was on September 9, 2001. I was climbing the stairs at the hospital on my way back to my office. I was on duty on the psychiatry consultation service. I happened to glance at the television in the lobby from the landing. A news story was showing one of the Twin Towers on fire.

I couldn’t believe my eyes. The rest of the day there was talk of the attack on America.

We visited New York City in 2017 and viewed the Memorial & Museum Plaza. We saw the Survivor Tree, the Callery Pear.

It seems like there is almost nothing else to remember about the date except the disaster and the tragedy.

But one of the local fire stations not far from our house has a Flag of Honor on the wall. It honors those killed in the terrorist attacks on 9/11.

Even if we can’t go to the Memorial in New York City, we can remember it and honor the brave.

CDC Update on SARS CoV-2 Variant BA.2.86

New update on the Covid-19 variant BA.2.86 as of Sept. 8, 2023. Highlights:

  • “The current increases in COVID-19 cases and hospitalizations in the United States are not being driven by BA.2.86 and instead are being caused by other predominantly circulating viruses.
  • Early research data from multiple labs are reassuring and show that existing antibodies work against the new BA.2.86 variant. These data are also encouraging because of what it may mean for the effectiveness of the 2023-2024 COVID-19 vaccine, which is currently under review. That’s because the vaccine is tailored to the currently circulating variants.
  • Since CDC’s initial risk assessment, BA.2.86 has been identified in additional countries from both human and wastewater specimens. The variant has been identified in nine U.S. states as of September 8, 2023, at 11:30 AM EDT— in people across Colorado, Delaware, Michigan, Ohio, Pennsylvania, Virginia, and Washington, as well as one additional human case that is being investigated. The variant has also been identified in wastewater samples in two states, New York and Ohio.
  • The U.S. SARS-CoV-2 Interagency Group (SIG) classified BA.2.86 as a Variant being Monitored (VBM) on September 1, 2023.”

CDC Update Today on Covid-19 Variant BA.2.86

Today’s update by the CDC on the Covid-19 variant BA.2.86 is at this link.

Highlights:

  • “The variant has been identified in at least four states in the United States in samples from either people or wastewater.
  • This variant is currently being studied in the laboratory to help understand how the immune system may interact with this virus.
  • The current increases in cases and hospitalizations in the United States are likely being driven by infections with XBB lineage viruses, not the new BA.2.86 variant.”

“CDC’s current assessment is that the updated COVID-19 vaccine, which will be available in mid-September, will likely be effective at reducing severe disease and hospitalization. Immune responses generated from prior infection also help protect against severe outcomes of COVID-19. There is currently no evidence that this variant is causing more severe illness. That assessment may change as additional scientific data are developed. CDC remains committed to releasing updates on trends and observations of this variant.”

Immune Impacts:  Approximately 97% of the U.S. population has antibodies to SARS-CoV-2 from vaccination, previous infection, or both (hybrid immunity). Immune responses to vaccines and infections are complex and involve both humoral (antibodies) and cellular immunity. It is likely that the humoral and cellular immune responses will continue to provide protection against severe disease from this variant. Laboratories are currently working on measuring antibody neutralization of BA.2.86 as well as other immune responses. This is an area of ongoing scientific investigation.

Therapeutics: The assessment as to the impact of BA.2.86 on currently approved or authorized therapeutics is unchanged. Examination of the mutation profile of BA.2.86 suggests that currently available treatments like nirmatrelvir-ritonavir (Paxlovid), remdesivir (Veklury), and molnupiravir (Lagevrio) will be effective against this variant. This assessment is from the SARS-CoV-2 Interagency Group (SIG), which comprises experts from multiple United States government agencies. Monitoring is ongoing, and CDC will update this document as additional data on the impact of this variant on therapeutics become available.”

CDC ACIP to Discuss Covid-19 Vaccines on September 12, 2023

The CDC Advisory Committee on Immunization Practices (ACIP) has a scheduled meeting on September 12, 2023 to discuss Covid-19 vaccines. The information about it is a bit difficult to find. It’s announced as a notice on the Federal Register. On the agenda:

Matters To Be Considered: The agenda will include discussion of COVID–19 vaccines. Recommendation votes for COVID–19 vaccines are scheduled. Agenda items are subject to change as priorities dictate. For more information on the meeting agenda, visit https://www.cdc.gov/vaccines/acip/meetings/index.html.

Clicking the link as of August 28, 2023 did not reveal a meeting agenda, but I expect this to be updated in the near future.

Sena Returning New Coffee Maker Today Already!

Well, Sena’s returning the new Mecity coffee maker today. Go figure, we just got it. There’s really nothing wrong with how it works. It’s a little tough to remove the pod after the brewing is done. It would be nice to have a machine able to make a full mug of coffee, which would mean a capacity exceeding the 10 oz limit.

I don’t know. It might have something to do with the extraterrestrial swimming in her cup.

Official CDC Update on New Covid-19 Variant BA.2.86

I’ve been looking for official CDC news about the new Covid-19 variant, BA.2.86 and it looks like it was just posted on their website yesterday.

Highlights:

“Last week, a new variant of SARS-CoV-2 called BA.2.86 was detected in samples from people in Denmark and Israel. At least two cases have been identified in the United States. This variant is notable because it has multiple genetic differences from previous versions of SARS-CoV-2.”

“Based on what CDC knows now, existing tests used to detect and medications used to treat COVID-19 appear to be effective with this variant. BA.2.86 may be more capable of causing infection in people who have previously had COVID-19 or who have received COVID-19 vaccines. Scientists are evaluating the effectiveness of the forthcoming, updated COVID-19 vaccine. CDC’s current assessment is that this updated vaccine will be effective at reducing severe disease and hospitalization. At this point, there is no evidence that this variant is causing more severe illness. That assessment may change as additional scientific data are developed. CDC will share more as we know more.”

Heat Joke Alert On the Loose!

The Excessive Heat Warning is still on, so you’re going to need another heat joke:

Knock, knock.

Who’s there?

Kenya.

Kenya who?

Kenya open the door so I can fix your air conditioner?

I’m hoping for your sake this will be the last heat joke alert.

Heat Joke Alert for Crying Out Loud!

The heat wave continues and the heat joke today is:

Q: What do we say about politicians during a heat wave?

A: It’s not the heat, it’s the stupidity.

The Heat Index could go as high as 114 degrees. The end might be in sight on Friday. Hang in there and stay cool.