CDC Advisory Committee Makes New Recommendations for RSV Vaccine

I looked at one slide set for the Respiratory Syncitial Virus (RSV) vaccine. I didn’t watch the meeting. The ACIP Adult RSV Work Group Clinical Considerations powerpoint presentation recommend transitioning away from the shared clinical decision-making (SCDM) component for getting the RSV vaccine.

Slide 4 seems clear:

“All adults aged 75 years and older should get a single dose of RSV vaccination.

All adults aged 60-74 years and with certain chronic medical conditions or other factors that increase the risk of severe RSV disease should receive a single dose of RSV vaccination.

These recommendations would replace the SCDM recommendation, meaning that adults aged 60-74 years without risk factors for severe RSV vaccine, are no longer recommended to receive RSV vaccination.”

Stat News has a report which includes comments on the unanimous vote in favor of the above.

What’s Up with Shared Clinical Decision Making for the RSV Vaccine?

There are probably some questions about the new Respiratory Syncitial Virus (RSV) vaccine. Because I’ve seen TV commercials about the new website RSVandMe, I checked on a few things the other day.

The RSVandMe website and the companion website are both produced by the RSV vaccine maker GlaxoSmithKline (GSK). As such, I consider them marketing commercials.

I checked the Centers for Disease Control (CDC) website and saw that the CDC Advisory Committee on Immunization Practices (ACIP) recommended approval of the RSV vaccine at their June Meeting (covered earlier on this blog):

Adults 60 years of age and older may receive a single dose of Respiratory Syncytial Virus (RSV) vaccine, using shared clinical decision-making.

The term “shared clinical decision-making” is clarified on the CDC webpage at this link.

The upshot of shared clinical decision-making is that it’s up to the provider (the list of providers include pharmacists). So far the list of recommended vaccines does not yet include RSV, so it probably needs updating. It looks like the ACIP MMWR recommendation page also needs updating.

Four Seasonal Vaccines for Older Adults?

There are a number of seasonal vaccines recommended for older adults in the U.S. They include vaccines for influenza, pneumonia, and the newest one is Respiratory Syncytial Virus (RSV).

I noticed that during the recent FDA meeting to decide on approval of another vaccine for the XBB variant of Covid-19, many experts objected to the use of the word “periodic” in the voting question.

Those objecting to it did so because of the implicit suggestion that Covid-19 is a seasonal virus. Not all experts agree on that. I gather it takes time to determine whether or not an infectious agent should be considered seasonal or not.

If the XBB variant of Covid-19, RSV, pneumonia, and influenza are all considered seasonal, then there are 4 vaccines for which older adults would be eligible.

The consensus among most experts is that you can take both influenza and Covid-19 vaccines at the same time. Most of us older adults also get the pnemococcal vaccine as well.

Will the RSV vaccine be added to the list? Should you get all 4 at the same time? Or should they be spaced out? Should you get the influenza and Covid-19 vaccines together and wait a week or two before getting the RSV and pneumococcal vaccines?

The increase in recommendations for vaccinations could be burdensome for those without health insurance. Vaccine uptake will probably continue to be a challenge.