Covid variant BA.2.86 – Go Retire Psychiatrist

New update on the Covid-19 variant BA.2.86 as of Sept. 8, 2023. Highlights:

“The current increases in COVID-19 cases and hospitalizations in the United States are not being driven by BA.2.86 and instead are being caused by other predominantly circulating viruses.
Early research data from multiple labs are reassuring and show that existing antibodies work against the new BA.2.86 variant. These data are also encouraging because of what it may mean for the effectiveness of the 2023-2024 COVID-19 vaccine, which is currently under review. That’s because the vaccine is tailored to the currently circulating variants.
Since CDC’s initial risk assessment, BA.2.86 has been identified in additional countries from both human and wastewater specimens. The variant has been identified in nine U.S. states as of September 8, 2023, at 11:30 AM EDT— in people across Colorado, Delaware, Michigan, Ohio, Pennsylvania, Virginia, and Washington, as well as one additional human case that is being investigated. The variant has also been identified in wastewater samples in two states, New York and Ohio.
The U.S. SARS-CoV-2 Interagency Group (SIG) classified BA.2.86 as a Variant being Monitored (VBM) on September 1, 2023.”

Today’s update by the CDC on the Covid-19 variant BA.2.86 is at this link.

Highlights:

“The variant has been identified in at least four states in the United States in samples from either people or wastewater.
This variant is currently being studied in the laboratory to help understand how the immune system may interact with this virus.
The current increases in cases and hospitalizations in the United States are likely being driven by infections with XBB lineage viruses, not the new BA.2.86 variant.”

“CDC’s current assessment is that the updated COVID-19 vaccine, which will be available in mid-September, will likely be effective at reducing severe disease and hospitalization. Immune responses generated from prior infection also help protect against severe outcomes of COVID-19. There is currently no evidence that this variant is causing more severe illness. That assessment may change as additional scientific data are developed. CDC remains committed to releasing updates on trends and observations of this variant.”

“Immune Impacts: Approximately 97% of the U.S. population has antibodies to SARS-CoV-2 from vaccination, previous infection, or both (hybrid immunity). Immune responses to vaccines and infections are complex and involve both humoral (antibodies) and cellular immunity. It is likely that the humoral and cellular immune responses will continue to provide protection against severe disease from this variant. Laboratories are currently working on measuring antibody neutralization of BA.2.86 as well as other immune responses. This is an area of ongoing scientific investigation.

Therapeutics: The assessment as to the impact of BA.2.86 on currently approved or authorized therapeutics is unchanged. Examination of the mutation profile of BA.2.86 suggests that currently available treatments like nirmatrelvir-ritonavir (Paxlovid), remdesivir (Veklury), and molnupiravir (Lagevrio) will be effective against this variant. This assessment is from the SARS-CoV-2 Interagency Group (SIG), which comprises experts from multiple United States government agencies. Monitoring is ongoing, and CDC will update this document as additional data on the impact of this variant on therapeutics become available.”