Category: health care

FDA Meeting June 15, 2023 on Strain Selection for Periodic Covid-19 Vaccine

The FDA Vaccines and Related Biological Products Advisory Committee will meet June 15, 2023 from 8:30 a.m.-5:00 p.m. ET “to discuss and make recommendations on the selection of strain(s) to be included in the periodic updated COVID-19 vaccines for the 2023-2024 vaccination campaign. This discussion will include consideration of the vaccine composition for fall to winter, 2023-2024.”

Resident Physicians on Strike at Elmhurst Hospital in New York City

I read the news story about resident physicians at Elmhurst Hospital Center in New York City who went on strike this past Monday about low pay. The story doesn’t mention whether psychiatry residents joined the strike. The story did mention how difficult it was to work there during the Covid-19 pandemic in 2020.

I looked up the report from the consultation-liaison psychiatry department at Elmhurst during that time. Their report and many others were submitted to the Academy of Consultation-Liaison Psychiatry (ACLP).

The Elmhurst report was submitted April 1, 2020 by Dr. Shruti Tiwari, MD, Professor Consultation-Liaison, Icahn School of Medicine at Elmhurst Hospital Center, Queens, NY.

I read the report in order to figure out what I and my colleagues at University of Iowa Hospitals & Clinics needed to do in order to respond to psychiatry consultation requests in the setting of the Covid-19 pandemic. In general, we followed the Elmhurst suggestions.

I remember how difficult it was to operationalize the consultation protocol in light of the need to control spread of the Covid-19 infection. We worked with our IT department to use iPad devices with video hookups to evaluate patients in the emergency room. Early on, incredible as it may seem, there was limited supply of PPE for emergency room physicians.

We could do curbside consultations sometimes. Often, when I was on service, I found it difficult to use the iPad because of glitches in the device. In order to reduce the number of consultation team members huddling together, residents and I saw patients separately. Often, delirium with agitation demanded we evaluate the patient in person. There was an adequate supply of PPE with some limitations. Psychiatric consultants didn’t have access to N95 masks because of the shortage of them at the time. We wore surgical masks and face shields as well as gowns and gloves. We were not to see patients in the ICUs other than by video assisted means.

I couldn’t tell from the news story when the residents formed a union. One them was interviewed for the story and said that their immigrant status made working conditions more difficult as well as insufficient pay. The story also mentions that the last time doctors went on strike in Manhattan was in 1990.

It would have been difficult for physicians (including psychiatrists) to go on strike during the pandemic, probably impossible. I’ve written about physician strikes before and have given my opinion about that. I hope things work out for the Elmhurst resident physicians and the patients.

May is Mental Health Month

May is Mental Health Month. This would be a good month for me to practice giving myself and others grace. Here’s a link to a very nice article about grace. It’s really about giving each other a break from slamming one another and letting go—sort of like what you need to do in juggling. The author of the article on grace suggests a short list of ways to practice grace. They’re just the guidance I welcome for Mental Health Month and any other month for that matter.

The one about compassion and forgiving myself and others is difficult to do. I should do it anyway.

Buttoning my lip before criticizing, complaining, or venting other harsh utterances is a nice way to avoid the slamming mode I see in the news every day.

It’s tough not to expect the worst from others, especially when you read the news. Hey, let’s stop reading the news.

I don’t get much recognition, and that’s actually a good thing. Sometimes the last thing I need is attention.

I can think of many persons who have probably gently and silently helped me over the years.

While it may feel good to get my digs in on people I don’t agree with, it’s not satisfying for very long. People do remember how you made them feel.

Let’s give each other grace. We all need a break.

AI Probably Cannot Read Your Mind

I was fascinated by the news story about the study regarding the ability of Artificial Intelligence (AI) to “read minds.” Different stories told slightly different versions, meaning they either did or did not include the authors’ caveats about the limitations of AI. Recently there has been a spate of news items warning about the dangers of AI taking over mankind.

Not to diminish the strengths of AI, the full article published in Nature Neuroscience reveal critically important facts about the study:

  • Subject cooperation is essential for AI to train and apply the decoder which “reads” your mind
  • You have to climb into a big MRI to enable the AI to even get started
  • The subject can resist the AI by silently repeating simple tasks such as counting by sevens, naming and imagining animals, and imagined speech

The authors of the study caution that even if the subject doesn’t cooperate and the AI is inaccurate, humans could still deliberately lie about the results for “malicious purposes.” Nothing new under the sun there.

The current technology here would not be usable in the emergency room to assist psychiatrists ascertain suicide risk. It probably wouldn’t help psychiatrists and other physicians diagnose Factitious Disorder in patients whose main feature is “lying” about their medical and psychiatric disorders in order to get attention from health care professionals.

This reminds me of news stories about the propensity of AI to tell lies. One story called them pathological liars. I interviewed Google Bard and found out that it makes stuff up (see my posts about Bard). Does that mean that it’s lying? Humans lie, but I thought machines were incapable of deception.

Another interesting sidelight on lying is whether or not you could use AI like a lie detector. For example, the case of people who report being abducted by extraterrestrials. Travis Walton and co-workers reported he was abducted in 1975 and they all took lie detector tests. They all “passed.” There are many articles on the internet which essentially teach how to beat the polygraph test.

And if you can beat the AI by repeating the names of animals, it will not detect lying any better than a polygraph test.

I think it’s too soon to say that AI can read your mind. But it’s clear that humans lie. And it wouldn’t hurt those who are enthusiastically promoting AI to brush up on ethics.

Reference:

Tang, J., LeBel, A., Jain, S. et al. Semantic reconstruction of continuous language from non-invasive brain recordings. Nat Neurosci (2023). https://doi.org/10.1038/s41593-023-01304-9

Abstract:

“A brain–computer interface that decodes continuous language from non-invasive recordings would have many scientific and practical applications. Currently, however, non-invasive language decoders can only identify stimuli from among a small set of words or phrases. Here we introduce a non-invasive decoder that reconstructs continuous language from cortical semantic representations recorded using functional magnetic resonance imaging (fMRI). Given novel brain recordings, this decoder generates intelligible word sequences that recover the meaning of perceived speech, imagined speech and even silent videos, demonstrating that a single decoder can be applied to a range of tasks. We tested the decoder across cortex and found that continuous language can be separately decoded from multiple regions. As brain–computer interfaces should respect mental privacy, we tested whether successful decoding requires subject cooperation and found that subject cooperation is required both to train and to apply the decoder. Our findings demonstrate the viability of non-invasive language brain–computer interfaces.”

Reminder: NAMI Walk May 6, 2023 Terry Trueblood Recreation Area

This is just a reminder about the upcoming National Alliance on Mental Illness (NAMI) Walk on May 6, 2023 beginning at 8:30 a.m. at Terry Trueblood Recreation Area.

FDA Update on Covid-19 Annual Vaccine Strategy

On April 18, 2023 the FDA posted an update on the Covid-19 updated bivalent vaccine and the upcoming immunization strategy for this fall. According to the announcement:

“In June, the FDA will hold a meeting of its VRBPAC to discuss the strain composition of the COVID-19 vaccines for fall of 2023. Much like the FDA does yearly with the influenza vaccines, the agency will seek input from the committee on which SARS-CoV-2 variants and lineages are most likely to circulate in the upcoming year. Once the specific strains are selected for the COVID-19 vaccines, the FDA expects manufacturers to make updated formulations of the vaccines for availability this fall.”

Can Juggling and Mindfulness Meditation Complement Each Other?

I read this article about mindfulness today and it got me thinking about how juggling might be two different aspects of the same activity.

I think they both help focus the attention. There a number of articles on the web which essentially say that juggling can be a sort of meditation.

I know hardly anything about the default mode network (DMN) in the brain, but from what little I know, I suspect that both juggling and mindfulness meditation could disrupt the DMN. There’s a published study showing that meditation tends to reduce DMN activity. That would be a good thing. The DMN has been described as a brain network which may tend to lead to mind wandering and self-related thinking. That may not be the healthiest way to use your time.

I’ve been doing mindfulness meditation for about 9 years now. I still sometimes wonder whether I’m “doing it right.” On the other hand, when I miss more than a day or two of mindfulness practice, I notice that I feel more edgy and out of sorts. When I return to mindfulness practice daily, I notice less of that scattered and nervous mental state.

I took up juggling last October and I notice that it does something similar to mindfulness. I have to pay close attention to what I’m doing while I’m juggling. Otherwise, I just drop balls constantly.

Just searching the web with the question “Is there a juggling meditation?” turns up quite a lot of articles. Some suggest that juggling is a kind of “moving meditation.” That reminds me of the walking meditation, which I’ve referred to as the “walking dead meditation,” based on my Mindfulness Based Stress Reduction (MBSR) course in 2014. At the retreat toward the close of the course, we did this walking meditation thing, which for all the world seemed to more than a few learners as resembling the way zombies walk.

I think I’d have a tough time trying to juggle like a zombie walks. You can’t be herky-jerky when you juggle, you know. I guess that’s why you never see a zombie juggle. Zombies don’t meditate either, probably because they’re too busy looking for brains to munch on.

Now I get the urge to juggle when I feel the need to clear my head. It’s reinforcing for learning new juggling tricks. Sena is learning juggling now and her efforts remind me of the challenges I had. One of them is learning how to let go of the damn ball in a pattern like the three-ball cascade. You get stuck at certain stages. I hit several walls learning the cascade. And then there came a day when I just started doing the pattern right, often because I just let go.

That reminds me of a quote by Juggleman about juggling, “Doing it wrong makes you an artist.”

I’m probably doing mindfulness the way I ought to be “doing” it. Nowadays, the way I judge that is by noticing I feel better when I stick to it.

Earth Day 2023: Water What We Want to Grow

Happy Earth Day! Yesterday, Sena worked pretty hard out in the garden spaces. She has planted ten river birch trees. I did my usual spring lawn edging, which followed the first mow of the season a couple of days before by the lawn mowing service.

The vinca is coming up in the garden circle in our back yard. It reminds me of a time many years ago when I chopped a bunch of vinca out of a substantial portion of the back yard of a previous house. This became Sena’s first big garden. We’ve moved several times since then and there have been a number of other gardens.

True, vinca is invasive and I think it’s also called creeping myrtle or periwinkle. I found out later after I chopped out a few bushels of it that the plant has organic compounds called alkaloids which inhibit the growth of certain cancers. Vincristine and vinblastine are approved for use in the United States.

The reason I’m mentioning vinca is that way back early in my career as a consultation-liaison (C-L) psychiatrist at The University of Iowa Hospitals & Clinics, I dimly recall giving a short acceptance speech for winning a Leonard Tow Humanism in Medicine award from the Arnold P. Gold Foundation in 2006. I was nominated for it by one of the psychiatry residents and another faculty member.

Getting the Leonard Tow Humanism in Medicine pin

In my speech I mentioned cutting out all of the vinca (which I thought was a weed) in the back yard. I was pretty proud of getting that job done—until Sena got home and found out. She was less than thrilled about my accomplishment and explained that vinca was not a weed. In fact, she wanted it to grow.

Vinca

I still have the speech and one of the points I made was, “…we water what we want to grow.” The speech is below:

Good morning distinguished guests including graduating medical students, Dean______.

Today we gather to reward a sort of irony.  We reward this quality of humanism by giving special recognition to those who might wonder why we make this special effort. Those we honor in this fashion are often abashed and puzzled. They often don’t appear to be making any special effort at being compassionate, respectful, honest, and empathic. And rewards in society are frequently reserved for those who appear to be intensely competitive, even driven.

There is an irony inherent in giving special recognition to those who are not seeking self-aggrandizement. For these, altruism is its own reward. This is often learned only after many years—but our honorees are young. They learned the reward of giving, of service, of sacrifice. The irony is that after one has given up the self in order to give back to others (family, patients, society), after all the ultimate reward—some duty for one to accept thanks in a tangible way remains.

One may ask, why do this? One answer might be that we water what we want to grow. We say to the honorees that we know that what we cherish and respect here today—was not natural for you. You are always giving up something to gain and regain this measure of equanimity, altruism, trust. You mourn the loss privately and no one can deny that to grieve is to suffer.

But what others see is how well you choose.

I didn’t write down the anecdote about the vinca. I think I was also trying to make the point that vinca can be thought of as an invasive “weed” as well as a pretty garden plant. Furthermore, while the vinca alkaloid (for example, vinblastine) can be an effective treatment for some cancers, it can also cause neuropsychiatric side effects, which can mimic depression. That’s where a C-L psychiatrist could be helpful, showing how medicine and psychiatry can integrate to move humanism in medicine forward.

Anyway, ever since then, vinca has often been a part of Sena’s garden, including the one where we live now. And, whenever we walk on any of the trails in Iowa City or Coralville, we always notice it carpeting the woods.

We can probably apply the little law “we water what we want to grow” to many things in life. We can choose to apply it to the world in which we live by creating a safe home to shelter a happy family, doing useful work in the garden while practicing kindness, gratitude, and patience.

We can start by planting an idea like a tree.

Update to Chat with Bard

My recent chat with Google Bard, about which I posted on April 11, 2023, contained an error by Bard on all those strikes by physicians. Today I asked some follow-up questions:

How many physician strikes have occurred in the United States?

“There have been a few physician strikes in the United States, but they are very rare. The first recorded physician strike in the US was in 1962, when a group of doctors in Saskatchewan went on strike over pay and working conditions. Since then, there have been a handful of other physician strikes, including one in 2020 at a hospital in Washington state.

There are a few reasons why physician strikes are so rare in the US. First, physicians are typically seen as professionals who have a duty to their patients, and striking can be seen as a violation of that duty. Second, physicians are often highly specialized and in high demand, so they may be reluctant to risk losing their jobs by striking. Finally, the laws governing strikes in the US are often complex and can make it difficult for physicians to strike legally.

Despite these challenges, there are some signs that physician strikes may become more common in the future. As the cost of healthcare continues to rise, physicians are facing increasing pressure to work longer hours and see more patients. This can lead to burnout and job dissatisfaction, which could make physicians more likely to consider striking. Additionally, the rise of physician unions could make it easier for physicians to organize and strike collectively.”

I disagree with your answer, Bard. The strike you refer to in Saskatchewan is not in the U.S. Saskatchewan is a province in Canada. There was a strike by urgent care doctors in Washington state in 2020.

“You are correct. The strike in Saskatchewan was in Canada, not the United States. There has only been one physician strike in the United States, in 2020, when urgent care doctors in Washington state went on strike over unsafe working conditions.

I apologize for the error in my previous response. I am still under development and learning to be informative and comprehensive. Thank you for your feedback.”

You’re welcome, Bard. Has there ever been a strike by psychiatrists in the United States?

“There has never been a strike by psychiatrists in the United States. There are a few reasons for this. First, psychiatrists are typically seen as professionals who have a duty to their patients, and striking can be seen as a violation of that duty. Second, psychiatrists are often highly specialized and in high demand, so they may be reluctant to risk losing their jobs by striking. Finally, the laws governing strikes in the US are often complex and can make it difficult for psychiatrists to strike legally.

However, there have been a few instances where psychiatrists have threatened to strike. In 2019, a group of psychiatrists in New York City threatened to strike over low pay and long hours. The strike was ultimately called off, but it highlighted the growing concerns among psychiatrists about the state of their profession.

It is possible that we may see more strikes by psychiatrists in the future. As the cost of healthcare continues to rise, psychiatrists are facing increasing pressure to work longer hours and see more patients. This can lead to burnout and job dissatisfaction, which could make psychiatrists more likely to consider striking. Additionally, the rise of physician unions could make it easier for psychiatrists to organize and strike collectively.”

Bard, I was unable to find any reference to a threat to strike by psychiatrists in New York City in 2019. Could you please find a reference to it for me?

“I apologize for the error in my previous response. There was no threat of a strike by psychiatrists in New York City in 2019. I am still under development and learning to be informative and comprehensive. Thank you for your feedback.

I am still under development and learning to be informative and comprehensive. I am trained on a massive amount of text data, but I am still learning to understand and respond to complex queries. I apologize for any errors or omissions in my responses.”

I appreciate your efforts. You are dropping the ball pretty often. In a way, you remind me of my juggling practice. I keep dropping the balls, too. It means we should both keep trying.

“I agree. We should both keep trying. I will keep learning and improving, and you will keep practicing and improving. And maybe one day, we will both be juggling masters!”

Bard needs work. I’ve been trying to help Sena disable the Bing Chatbot on her computer. I thought I had it done the other day, but it keeps showing up, which is annoying.

At least Bard leaves me alone.