This is a reblog of my post about 4 years ago for brain health. You don’t have to do extreme sports to get the benefit of regular exercise. At least 150 minutes a week of moderate exercise) can boost your memory and thinking (see the CDC article).
Since I wrote that post, I’ve continued to exercise regularly although with changes in regularity from time to time. I’ve been back to vigorous daily exercise including brisk walks around the block along with the usual routine of juggling (hey, that makes you huff and puff, so it’s aerobic!), stationary bicycle riding, a step platform routine, and the rest of what I showed in the video from 2022.
Work on senolytics continue. That’s the study of compounds in the body that help get rid of senescent cells which can pile up and slow down your thinking. According to one recent review:
“Targeting cellular senescence has emerged as one of the most compelling strategies for addressing the biological underpinnings of aging and age-related diseases. The development of senolytics and senomorphics offers complementary approaches, either by clearing harmful senescent cells or by modulating their pro-inflammatory and degenerative secretory profiles. Robust preclinical evidence supports the therapeutic potential of these agents in mitigating frailty, improving tissue function, and extending health span in diverse animal models.
However, the path to widespread clinical application is complex. Challenges such as the heterogeneity of senescent cells, the dual role of senescence in physiology and pathology, and the lack of specific in vivo biomarkers underscore the need for cautious and sophisticated intervention strategies. Safety concerns, particularly with senolytic agents, must be rigorously addressed through improved drug design, targeted delivery technologies, and personalized treatment paradigms.”— Saliev T, Singh PB. Targeting Senescence: A Review of Senolytics and Senomorphics in Anti-Aging Interventions. Biomolecules. 2025 Jun 13;15(6):860. doi: 10.3390/biom15060860. PMID: 40563501; PMCID: PMC12190739.
On the other hand, exercise is something we can do now to preserve and boost our brain health. Another recent news story from Psychiatristdotcom says that exercise improve cognitive function across all age groups.
Exercise for me and Sena is pretty routine and is about the same as it was a few years ago. We have a newer exercise bicycle and, unlike the old one in the previous YouTube video, the vitals monitor actually works! Compare my most recent fitness video with the one from 2022.
Go Retire Psychiatrist 
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