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FDA Approves Antipsychotic with New Mechanism of Action for Treatment of Schizophrenia
I just noticed the FDA announcment of the approval of an antipsychotic with a new mechanism of action for the treatment of schizophrenia. The drug is Cobenfy and it interacts with cholinergic rather than dopaminergic receptors. It has a number of side effects which are anticholinergic. This could lead to psychotic symptoms that consultation-liaison psychiatrists…
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Notes on the Blues and Rivers of Whiskey
I listened to the Big Mo Blues Show last night on KCCK radio (88.3 on your dial) as I usually do on Friday nights. It runs from 6:00 pm to 9:00 pm and you can learn a lot from Big Mo (aka John Heim) about the blues. He also has a podcast called the Big…
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Thoughts on X-Files Episode “Sunshine Days”
I saw the X-Files episode “Sunshine Days” again last night. It’s the second time I’ve seen it. It’s about a guy who calls himself Oliver who has telekinetic power and who yearns for a father-son relationship with a paranormal researcher (Dr. Reitz) who studied him when he was a kid named Anthony. The set…
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Bathroom Fan Timers are Now Required by Code!
OK, so maybe you already knew that bathroom exhaust fan timers for reducing moisture are required by code. But we didn’t, which is why we were both a little spooked when the hallway bathroom fan came on all by itself on our first evening in our new house. It has done that a few times,…
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Thoughts on the Homeless Mentally Ill
The homeless man who lives on the sidewalk outside our hotel reminds me of a couple of things. One is Dr. Gerard Clancy, MD who is University of Iowa Health Care Professor of Psychiatry, Professor of Emergency Medicine, and Senior Associate Dean of External Affairs. I remember Gerry, who was in the department of psychiatry…
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Alcohol is Bad for Old Guys
I took a quick peek at the study published recently in the Journal of the American Medical Association (JAMA) that a few news agencies are reporting on which says alcohol in moderation is bad for older persons. So much for moderation. Actually, the full abstract is: Ortolá R, Sotos-Prieto M, García-Esquinas E, Galán I, Rodríguez-Artalejo F. Alcohol Consumption Patterns…
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Thoughts About Psychedelic Assisted Psychotherapy
I read the Psychiatric Times article “FDA Issues CRL to Lykos for MDMA-Assisted Therapy.” The short story is that the FDA essentially told the drug company Lykos that their study of the efficacy of MDMA-assisted treatment of PTSD needs more work. I tried to wade through the on-line documents of the FDA’s meeting on June…



